Neighborhood guide · Panama City

Santa Ana Restaurants: 12 spots

Santa Ana has 12 restaurants on EatsPanama, spanning Spanish, Pizza. Each listing is built from public sources and menus - no restaurant can pay to appear here.

No paid rankings, everHours checked Jul 2026
BakeryPizzaSpanishBarInternationalCafe
The colonial Iglesia de Santa Ana and its plaza in the historic Santa Ana district, Panama City

The full list

All 12 places to eat in Santa Ana

Every place in Santa Ana, A to Z. Each listing is built from public sources - menu, hours and details - with no paid placement.

Plated dish at Napoli, Santa Ana, Panama City

Restaurante Napoli y Pizzería

Pizza·$$·a un costado del Instituto Nacional

La Musa Bar & Lounge

Spanish·Santa Ana

Nelson Café

International·$·Av. Central España 18

Astoria Restaurante Café Bar

Cafe·XF65+2RP

Bahia Beach

Bar·$·XF55+FVV

Coliseo Night Club

Bar·XF55+CRR

Delicias Pinoleras

International·C. H

Discoteca Night Club los Pepes

Bar·$$·XF55+JVQ Discoteca night club los pepe

Dulcería Dulcerama

Bakery·$·C. 17 Oeste

McDonald's Peatonal

International·$·Av. Central España

Panaderia El Palacio Del Pan

Bakery·$·C. 18 Este

Salon Maravilla

Bar·$·XF55+CQP

Go deeper

Browse by cuisine in Santa Ana

Each cuisine has its own page for this neighborhood.

Bakery 2 placesPizza 1 placesSpanish 1 placesBar 4 placesInternational 3 placesCafe 1 placesAll Panama City 1297 places

Before you go

Santa Ana dining, answered

What is the best restaurant in Santa Ana?

There is no single best - it depends on the night. Well-known Santa Ana spots include La Musa Bar & Lounge, Restaurante Napoli y Pizzería, McDonald's Peatonal. Every listing here is built from public information and updated monthly.

How expensive is eating in Santa Ana?

Places on this list run $ to $$. Where menus are published, mains typically fall between $7.75 and $12.50.

Do I need reservations in Santa Ana?

Friday and Saturday nights, yes - most rooms are small and fill early. 0 of the 12 listed spots take bookings over WhatsApp; the green button on each card starts the chat.

Where can I eat late in Santa Ana?

Most kitchens in the neighborhood close between 9 and 11 PM. Hours are shown on each listing.

Keep exploring

From the guides

All 3 guides →